Title

Respiratory Syncytial Virus Infections: Recent Prospects for Control

Document Type

Article

Journal/Book Title/Conference

Antiviral Research

Volume

71

Issue

2-3

Publisher

Elsevier

Publication Date

2006

First Page

379

Last Page

390

DOI

10.1016/j.antiviral.2006.05.014

Abstract

Respiratory syncytial virus (RSV) infections remain a significant public health problem throughout the world, although recently developed and clinically approved anti-RSV antibodies administered prophylactically to at-risk populations appear to have significantly affected the disease development. Much effort has been expended to develop effective anti-RSV therapies, using both in vitro assay systems and mouse, cotton rat, and primate models, with several products now in various stages of clinical study. Several products are also being considered for the treatment of clinical symptoms of RSV. In this review, updates on the status of the approved anti-RSV antibodies, ribavirin, and recent results of studies with potential new anti-RSV compounds are summarized and discussed.