Title

Interactions of Calcium and Cyclic AMP Signaling Pathways Regulating Steroidogenesis in Primary Cultured Theca and Granulosa Cells of Atlantic Croaker

Document Type

Article

Journal/Book Title/Conference

Fish Physiology and Biochemistry

Volume

28

Issue

1/4

Publisher

Springer Verlag

Publication Date

3-2003

First Page

327

Last Page

328

DOI

DOI: 10.1023/B:FISH.0000030572.66804.65

Abstract

The function of adenylyl cyclase (AC)-dependent and calcium (Ca2+)-dependent signal transduction pathways in mediating gonadotropin-stimulated testosterone (T) synthesis in croaker follicular cells was investigated. Both pathways are critical regulators of steroidogenesis in these cells. Stimulation of steroidogenesis by modulators of AC-dependent cell signaling is partially dependent on the presence of extracellular Ca2+, although AC function does not appear to be mediated by the Ca2+ pathway in croaker follicular cells.

Comments

The original publication is available at www.springerlink.com