Interactions of Calcium and Cyclic AMP Signaling Pathways Regulating Steroidogenesis in Primary Cultured Theca and Granulosa Cells of Atlantic Croaker

Authors

Abby D. Benninghoff, Utah State UniversityFollow
P. Thomas

Document Type

Article

Journal/Book Title/Conference

Fish Physiology and Biochemistry

Volume

28

Issue

1/4

Publisher

Springer Verlag

Publication Date

3-2003

First Page

327

Last Page

328

Abstract

The function of adenylyl cyclase (AC)-dependent and calcium (Ca²⁺)-dependent signal transduction pathways in mediating gonadotropin-stimulated testosterone (T) synthesis in croaker follicular cells was investigated. Both pathways are critical regulators of steroidogenesis in these cells. Stimulation of steroidogenesis by modulators of AC-dependent cell signaling is partially dependent on the presence of extracellular Ca²⁺, although AC function does not appear to be mediated by the Ca²⁺ pathway in croaker follicular cells.

Comments

The original publication is available at www.springerlink.com

Recommended Citation

Benninghoff, A. and P. Thomas (2003) Interactions of calcium and cyclic AMP signaling pathways regulating steroidogenesis in primary cultured theca and granulosa cells of Atlantic croaker. Fish Physiology and Biochemistry 28 (1-4): 327-328.