Conventional spontaneous Raman micro-spectroscopy was used for the investigation of bone and calcium phosphate coatings on bone-implant surfaces. Chemical and structural changes at the bone-coating interface could be monitored on a microscopic scale. It was shown that the crystallinity did not vary within the crystalline apatite and amorphous calcium phosphate coatings, while the density within each coating did vary. Different degrees of crystallinity in coatings were investigated for a series of plasma-sprayed apatite coatings. It is concluded that Raman microspectroscopy is an easy non-destructive way to obtain information about the apatite structure and the degree of crystallinity.
de Grauw, C. J.; de Bruijn, J. D.; Otto, C.; and Greve, J.
"Investigation of Bone and Calcium Phosphate Coatings and Crystallinity Determination Using Raman Microspectroscopy,"
Cells and Materials: Vol. 6
, Article 6.
Available at: http://digitalcommons.usu.edu/cellsandmaterials/vol6/iss1/6