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2012
Flip-Teaching: Preliminary Findings of a Study with an Undergraduate Organic Chemistry Class, Mike A. Christiansen
A simple Arg to Lys mutant of protein phosphatase 1 exhibits catalytic efficiencies toward monoanionic substrates superior to wild type, Yuan Chu, Nicholas H. Williams, and Alvan C. Hengge
Less Cookbook and More Research: The Total Syntheses of JBIR-94 and JBIR-125, Student-Designed Research Projects Conducted in a Sophomore Organic Chemistry Lab, C. L. Crawford and Mike A. Christiansen
The phosphoramidase competency of prototypical phosphatase motifs, Mark P. Haney and Alvan C. Hengge
Production of the Industrial Feedstock Chemical HMF From Algae, Kelsey Klemm, J. Tyler Gish, Emily Measom, and Alvan C. Hengge
High resolution structure of the phosphatase VHZ explains unexpected substrate specificity, and suggests the presence of metavanadate at the active site, Viacheslav I. Kuznetsov, Sean J. Johnson, and Alvan C. Hengge
2011
Elucidation of promiscuous catalytic activity of pseudomonas aeruginosa sulfatase, Ryan D. Berry, Kelsey V. Klemm, and Alvan C. Hengge
2010
Mechanistic study of phosphoryl transfer reactions catalyzed by protein phosphatase-1, Yuan Chu, Nicholas H. Williams, and Alvan C. Hengge
Protein Motions in Catalysis by Protein Tyrosine Phosphatases, Alvan C. Hengge
Kinetic studies of the dual-specificity phosphatase VHZ, Vyacheslav I. Kuznetsov and Alvan C. Hengge
2009
Analogous Mutations in Two PTP Enzymes Cause Differential Adverse Effects on Catalysis, Ryan D. Berry, Sara A. Huefner, Tiago A. Brandão, and Alvan C. Hengge
Phase-transfer catalyzed asymmetric synthesis of S-naproxen, M. A. Binkley, M. A. Christiansen, K. H. Harper, and M. B. Andrus
Phase-transfer catalyzed synthesis of the Soy isoflavanoid S-Equol, A. W. Butler, A. L. Calvert, M. A. Christiansen, and M. B. Andrus
Synthesis of 12-HETE using asymmetric phase-transfer catalysis, M. A. Christiansen and M. B. Andrus
Synthesis of kurasoin B analogs, J. R. Nielson, M. A. Christiansen, and M. B. Andrus
2008
Asymmetric acylimidazole alkylation under phase-transfer conditions, M. A. Christiansen and M. B. Andrus
Differential Mutational Effects on Conformational Changes During Catalysis by Protein-Tyrosine Phosphatases, Alvan C. Hengge, Tiago A. Brandão, Sara A. Huefner, and Sean J. Johnson
Protein-Tyrosine Phosphatases: Comparing the Effects of Mutation on Protein Conformation and Catalysis, Sara A. Huefner, Tiago A. Brandão, Sean J. Johnson, and Alvan C. Hengge
Mutations of critical amino acids in the human enzyme PTP1B, Sara A. Huefner and Alvan C. Hengge
2007
Diesterase Activity and Substrate Binding in Purple Acid Phosphatases, Alvan C. Hengge
Effect of thio-substitution on the mechanisms of transesterification of ribonucleoside phosphodiester models, Subashree Iyer and Alvan C. Hengge
Mechanistic study of PP-1, a catalytically promiscuous enzyme, Elizabeth A. Lund, Alvan C. Hengge, Nicholas H. Williams, Claire McWhirter, and Guoqiang Feng
Comparative mechanistic studies on the catalytically promiscuous serine/threonine protein phosphatase-1 (PP-1) and the dinuclear cobalt(III) complex [Co2(tacn)2(OH)3](ClO4)3, Eric A. Tanifum, Alvan C. Hengge, Elizabeth A. Lund, Nicholas H. Williams, and Guoqiang Feng
2006
Kinetic Isotope Effects on the Reactions of Purple Acid Phosphatases, Robynn Cox and Alvan C. Hengge
Mechanism of Phosphotriester Hydrolysis by Pyrazolylborate Zinc Hydroxide Complex, Alvan C. Hengge
Metals in Phosphoryl Transfer: From Model Systems to Purple Acid Phosphatases, Alvan C. Hengge
2005
The Effect of Metal Ions on Phosphoryl Transfer Reactions, Alvan C. Hengge
Use of 18O isotope Shifts on 31P NMR to Probe Potential Medium Effects on Phosphate Ester Bond Strengths, K. Sorensen-Stowell and Alvan C. Hengge
2004
Kinetic and Spectroscopic Investigations of Phosphate and Thiophosphate Esters, J. Purcell and Alvan C. Hengge
Use of 18O Isotopic Shifts in 31P NMR for Determination of P-O Bond Order of Various Phosphate Esters in Water, K. Sorensen-Stowell and Alvan C. Hengge
Aryloxymethano- and Aryloxyethano-Phosphonic Acids and Their Analogues as Motifs for Inhibition of Phosphatases, J. M. Younker, S. S. Iyer, P. G. Czyryca, and Alvan C. Hengge
2003
HyperChem™ as a Programming Environment for De Novo Methodology, P. G. Czyryca and Alvan C. Hengge
Phosphonoethers: Analogs of the Phosphoryl Transfer Transition State, P. G. Czyryca, J. Younker, S. Iyer, and Alvan C. Hengge
Altered Hydrolysis Mechanisms for a Metal-Complexed Phosphate Monoester and Diester, Alvan C. Hengge
Recent Studies of Phosphoryl Transfer Mechanisms, Alvan C. Hengge
Altered Hydrolysis Mechanisms for a Metal-Complexed Phosphate Monoester and Diester, Alvan C. Hengge, T. Humphry, M. Forconi, and N. H. Williams
Alteration of the mechanisms of phosphate ester hydrolysis by complexation to a dinuclear metal center, T. Humphry, M. Forconi, N. H. Williams, and Alvan C. Hengge
Synthesis and evaluation of aryloxymethyl and aryloxyethyl phosphonates as inhibitors of phosphatases, S. S. Iyer, J. M. Younker, P. G. Czyryca, and Alvan C. Hengge
The Transition State for Thiophosporyl Transfer from Aryl Dimethylphosphinothioates to Oxygen Nucleophiles in Aqueous Solution, I. Onyido, K. Swierczek, and Alvan C. Hengge
Mechanistic studies of phosphoryl and thiophosphoryl group transfer, J. Purcell and Alvan C. Hengge
Comparison of phosphonothioic acids with phosphonic acids as inhibitors of phosphatases, K. J. Swierczek and Alvan C. Hengge
Mechanistic Study of Aryl Aryl Sulfate Diesters, J. Younker and Alvan C. Hengge
2002
Kinetic Isotope Effect Studies of the Phosphoryl Transfer Reaction, P. G. Czyryca and Alvan C. Hengge
Are Phosphorothioates Valid Mechanistic Probes for Enzymatic Phosphoryl Transfer?, Alvan C. Hengge
Mechanism of Reaction of Phosphate Esters Coordinated to a Model of Dinuclear Metallophosphatases, T. Humphry, M. Forconi, N. H. Williams, and Alvan C. Hengge
2001
A Novel Motif for the Design of Transition State Analogs for Phosphatases, P. G. Czyryca and Alvan C. Hengge
Medium Effects on Phosphoryl Transfer Reactions and Their Possible Applicability to Enzymatic Phosphoryl Transfer, P. Grzyska, P. Czyryca, J. Golightly, K. Small, and P. Larsen
Isotope Effects in Enzymatic Reactions of Phosphorothioates, Alvan C. Hengge
Transition States for Phosphoryl Transfer Reactions of Phosphatases and Their Application to Inhibitor Design, Alvan C. Hengge
Mechanism of Reaction of Phosphate Esters Coordinated to a Model of Dinuclear Metallophosphatases, T. Humphry, M. Forconi, Alvan C. Hengge, and N. H. Williams
2000
Medium Effects in Phosphoryl Transfer Reactions: Information from Isotope Effects, Theoretical Studies, Kinetics, and Thermodynamics, P. Grzyska, P. Czyryca, R. Hoff, K. Small, and Alvan C. Hengge
Does the Transition State for Sulfuryl Transfer Resemble That for Phosphoryl Transfer?, R. Hoff and Alvan C. Hengge
1999
Does Positive Charge at the Active Sites of Phosphatases Cause a Change in Mechanism?, Alvan C. Hengge
The Transition State of the Phosphoryl Transfer Reaction Catalyzed by the Lambda Ser/Thr Protein Phosphatase, Alvan C. Hengge
The Role of the Active Site Arginine in a Protein-Tyrosine Phosphatase. Does Positive Charge Cause a Change in Mechanism for Enzymatic Phosphoryl Transfer?, Alvan C. Hengge, R. H. Hoff, L. Wu, B. Zhou, and Z. Y. Zhang
The Effect on the Function of the General acid Catalyst from Mutations of the Invariant Tryptophan and Arginine Residues in the Protein- Tyrosine Phosphatase from Yersinia, R. H. Hoff, Alvan C. Hengge, Y. F. Keng, and Z. Y. Zhang
A Model for the Catalytic Mechanism of the Metallophosphatases Calcineurin and λ Protein Phosphatase: Studies from Mutants Lacking an Active Site Histidine, P. Mertz, R. H. Hoff, F. Rusnak, and Alvan C. Hengge
A Model for the Catalytic Mechanism of the Metallophosphatases Calcineurin and λ Protein Phosphatase: Studies from Mutants Lacking an Active Site Histidine, P. Mertz, R. H. Hoff, F. Rusnak, and Alvan C. Hengge
Co(III) and Zn(II) Catalyzed Hydrolysis of Phosphodiesters, J. Rawlings, Alvan C. Hengge, and W. W. Cleland
The Transition State of the Reaction Catalyzed by Bacteriophage λ Protein Phosphatase, F. Rusnak, R. H. Hoff, P. Mertz, and Alvan C. Hengge
1998
Insights from Heavy-Atom Isotope Effects on Sulfuryl and Phosphoryl Transfer Reactions, Alvan C. Hengge
1997
Thermodynamics, pH Behavior, and Effect of Metal Ions in Reactions of Phosphorothioates, I. E. Catrina and Alvan C. Hengge
Thermodynamics of Solvation Effects on Phosphoryl and Sulfuryl Transfer Reactions, R. H. Hoff and Alvan C. Hengge
Co(III)-Cyclen Catalyzed Hydrolysis of p-Nitrophenyl Phosphate, J. Rawlings and Alvan C. Hengge
1996
Phosphoryl Transfer Reactions of Protein Phosphatases, Alvan C. Hengge
1995
Kinetic Isotope Effects on Reactions of Tyrosine Phosphatases, Alvan C. Hengge and Z. Y. Zhang
1994
Isotope Effects on the Hydrolysis of Cobalt (II)- Bound Phosphate Esters, J. Rawlings, Alvan C. Hengge, and W. W. Cleland
1993
Mechanistic Probes of Acyl and Phosphoryl Transfer Reactions Using Heavy Atom Isotope Effects, Alvan C. Hengge, R. A. Hess, A. E. Tobin, and W. W. Cleland
1992
Concertedness in Acyl Transfer Reactions of Esters, Alvan C. Hengge
1991
Solution and Enzymatic Phosphoryl Transfer Reactions of Phosphodiesters: Characterization of Transition States by Heavy Atom Isotope Effects, Alvan C. Hengge and W. W. Cleland
1990
Determination of the Transition States for Phosphoryl Transfer and Hydrolysis Reactions, Alvan C. Hengge and W. W. Cleland
Secondary Oxygen-18 Isotope Effects on Phosphodiester Hydrolysis Reactions, Alvan C. Hengge and W. W. Cleland
1986
Oxidative Condensation Reactions Based Upon Triazolinedione Ylides, Alvan C. Hengge and R. M. Wilson
1905
Solution and Enzymatic Reactions of Phosphorothioate Monoesters: Thermodynamics and Mechanisms, I. E. Catrina and Alvan C. Hengge
Entropy Effects in the Catalytic Efficiencies of Phosphatases, R. H. Hoff and Alvan C. Hengge
The catalytic mechanism of purple acid phosphatases, N. Mitic, R. S. Cox, M. Lanznaster, L. R. Gahan, and A. Neves