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2007
Mechanistic study of PP-1, a catalytically promiscuous enzyme, Elizabeth A. Lund, Alvan C. Hengge, Nicholas H. Williams, Claire McWhirter, and Guoqiang Feng; 233rd ACS National Meeting, Chicago, IL
Comparative mechanistic studies on the catalytically promiscuous serine/threonine protein phosphatase-1 (PP-1) and the dinuclear cobalt(III) complex [Co2(tacn)2(OH)3](ClO4)3, Eric A. Tanifum, Alvan C. Hengge, Elizabeth A. Lund, Nicholas H. Williams, and Guoqiang Feng; 234th American Chemical Society National Meeting, Boston, MA
2006
Kinetic Isotope Effects on the Reactions of Purple Acid Phosphatases, Robynn Cox and Alvan C. Hengge; Gordon Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
Mechanism of Phosphotriester Hydrolysis by Pyrazolylborate Zinc Hydroxide Complex, Alvan C. Hengge; Gordon Research Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
Metals in Phosphoryl Transfer: From Model Systems to Purple Acid Phosphatases, Alvan C. Hengge; ComBio meeting of the Australian Society for Biochemistry and Molecular Biology, in Brisbane, Australia
2005
The Effect of Metal Ions on Phosphoryl Transfer Reactions, Alvan C. Hengge; Isotopes 2005 Conference, Bath, UK
Use of 18O isotope Shifts on 31P NMR to Probe Potential Medium Effects on Phosphate Ester Bond Strengths, K. Sorensen-Stowell and Alvan C. Hengge; 229th ACS National Meeting, in San Diego, CA
2004
Kinetic and Spectroscopic Investigations of Phosphate and Thiophosphate Esters, J. Purcell and Alvan C. Hengge; Joint 59th Northwest and 18th Rocky Mountain Regional Meeting of the American Chemical Society, Logan Utah
Use of 18O Isotopic Shifts in 31P NMR for Determination of P-O Bond Order of Various Phosphate Esters in Water, K. Sorensen-Stowell and Alvan C. Hengge; Gordon Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
Aryloxymethano- and Aryloxyethano-Phosphonic Acids and Their Analogues as Motifs for Inhibition of Phosphatases, J. M. Younker, S. S. Iyer, P. G. Czyryca, and Alvan C. Hengge; Undergraduate Research Day at the State Capitol, Utah State Capitol
2003
HyperChem™ as a Programming Environment for De Novo Methodology, P. G. Czyryca and Alvan C. Hengge; Structure-Based Drug Design 2003, Boston, MA
Phosphonoethers: Analogs of the Phosphoryl Transfer Transition State, P. G. Czyryca, J. Younker, S. Iyer, and Alvan C. Hengge; Structure-Based Drug Design 2003, Boston, MA
Recent Studies of Phosphoryl Transfer Mechanisms, Alvan C. Hengge; McMaster University, Hamilton, Ontario
Altered Hydrolysis Mechanisms for a Metal-Complexed Phosphate Monoester and Diester, Alvan C. Hengge, T. Humphry, M. Forconi, and N. H. Williams; International Isotope Effects Conference, Uppsala. Sweden
Alteration of the mechanisms of phosphate ester hydrolysis by complexation to a dinuclear metal center, T. Humphry, M. Forconi, N. H. Williams, and Alvan C. Hengge; 226th ACS National Meeting, New York, NY
Synthesis and evaluation of aryloxymethyl and aryloxyethyl phosphonates as inhibitors of phosphatases, S. S. Iyer, J. M. Younker, P. G. Czyryca, and Alvan C. Hengge; 226th ACS National Meeting, New York, NY
The Transition State for Thiophosporyl Transfer from Aryl Dimethylphosphinothioates to Oxygen Nucleophiles in Aqueous Solution, I. Onyido, K. Swierczek, and Alvan C. Hengge; 39th IUPAC Congress and 86th Conference of The Canadian Society for Chemistry, Ottawa, Canada
Mechanistic studies of phosphoryl and thiophosphoryl group transfer, J. Purcell and Alvan C. Hengge; 226th ACS National Meeting, New York, NY
Comparison of phosphonothioic acids with phosphonic acids as inhibitors of phosphatases, K. J. Swierczek and Alvan C. Hengge; 226th ACS National Meeting, New York, NY
Mechanistic Study of Aryl Aryl Sulfate Diesters, J. Younker and Alvan C. Hengge; National Conference on Undergraduate Research, University of Utah
2002
Kinetic Isotope Effect Studies of the Phosphoryl Transfer Reaction, P. G. Czyryca and Alvan C. Hengge; Gordon Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
Are Phosphorothioates Valid Mechanistic Probes for Enzymatic Phosphoryl Transfer?, Alvan C. Hengge; Physical Chemistry Division Symposium on Modern Aspects of Structure Function Correlations of Biomolecules: Phosphoryl and Nucleotidyl Transfer Reactions, 223d National Meeting of the ACS, Orlando
Mechanism of Reaction of Phosphate Esters Coordinated to a Model of Dinuclear Metallophosphatases, T. Humphry, M. Forconi, N. H. Williams, and Alvan C. Hengge; Gordon Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
2001
A Novel Motif for the Design of Transition State Analogs for Phosphatases, P. G. Czyryca and Alvan C. Hengge; 222nd National Meeting of the ACS, Chicago, IL
Medium Effects on Phosphoryl Transfer Reactions and Their Possible Applicability to Enzymatic Phosphoryl Transfer, P. Grzyska, P. Czyryca, J. Golightly, K. Small, and P. Larsen; 222nd National Meeting of the ACS, Chicago, IL
Isotope Effects in Enzymatic Reactions of Phosphorothioates, Alvan C. Hengge; An Isotope Odyssey, Zakopane, Poland
Transition States for Phosphoryl Transfer Reactions of Phosphatases and Their Application to Inhibitor Design, Alvan C. Hengge; Metals in Medicine Symposium, 222nd National Meeting of the ACS, Chicago
Mechanism of Reaction of Phosphate Esters Coordinated to a Model of Dinuclear Metallophosphatases, T. Humphry, M. Forconi, Alvan C. Hengge, and N. H. Williams; 222nd National Meeting of the ACS, Chicago, IL
2000
Medium Effects in Phosphoryl Transfer Reactions: Information from Isotope Effects, Theoretical Studies, Kinetics, and Thermodynamics, P. Grzyska, P. Czyryca, R. Hoff, K. Small, and Alvan C. Hengge; Gordon Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
Does the Transition State for Sulfuryl Transfer Resemble That for Phosphoryl Transfer?, R. Hoff and Alvan C. Hengge; Gordon Conference on Isotopes in Biological and Chemical Sciences, Ventura, CA
1999
Does Positive Charge at the Active Sites of Phosphatases Cause a Change in Mechanism?, Alvan C. Hengge; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY
The Transition State of the Phosphoryl Transfer Reaction Catalyzed by the Lambda Ser/Thr Protein Phosphatase, Alvan C. Hengge; 16th Enzyme Mechanisms Conference, Napa, CA
The Role of the Active Site Arginine in a Protein-Tyrosine Phosphatase. Does Positive Charge Cause a Change in Mechanism for Enzymatic Phosphoryl Transfer?, Alvan C. Hengge, R. H. Hoff, L. Wu, B. Zhou, and Z. Y. Zhang; Gordon Conference on Enzymes, Coenzymes and Metabolic Pathways, Meriden, New Hampshire
The Effect on the Function of the General acid Catalyst from Mutations of the Invariant Tryptophan and Arginine Residues in the Protein- Tyrosine Phosphatase from Yersinia, R. H. Hoff, Alvan C. Hengge, Y. F. Keng, and Z. Y. Zhang; 16th Enzyme Mechanisms Conference, Napa, CA
A Model for the Catalytic Mechanism of the Metallophosphatases Calcineurin and λ Protein Phosphatase: Studies from Mutants Lacking an Active Site Histidine, P. Mertz, R. H. Hoff, F. Rusnak, and Alvan C. Hengge; Thirteenth Symposium of the Protein Society, Boston, MA
Co(III) and Zn(II) Catalyzed Hydrolysis of Phosphodiesters, J. Rawlings, Alvan C. Hengge, and W. W. Cleland; 217th American Chemical Society National Meeting, Anaheim, CA
The Transition State of the Reaction Catalyzed by Bacteriophage λ Protein Phosphatase, F. Rusnak, R. H. Hoff, P. Mertz, and Alvan C. Hengge; International Conference on Biological Inorganic Chemistry, Minneapolis, Minnesota
1998
Insights from Heavy-Atom Isotope Effects on Sulfuryl and Phosphoryl Transfer Reactions, Alvan C. Hengge; Gordon Research Conference on Isotopes in Biological and Chemical Sciences
1997
Thermodynamics, pH Behavior, and Effect of Metal Ions in Reactions of Phosphorothioates, I. E. Catrina and Alvan C. Hengge; American Chemical Society National Meeting, Las Vegas, Nevada
Thermodynamics of Solvation Effects on Phosphoryl and Sulfuryl Transfer Reactions, R. H. Hoff and Alvan C. Hengge; American Chemical Society National Meeting, Las Vegas, Nevada
Co(III)-Cyclen Catalyzed Hydrolysis of p-Nitrophenyl Phosphate, J. Rawlings and Alvan C. Hengge; American Chemical Society National Meeting, San Francisco, CA
1996
Phosphoryl Transfer Reactions of Protein Phosphatases, Alvan C. Hengge; Gordon Research Conference on Isotopes in Biology and Chemistry, Ventura, CA
1995
Kinetic Isotope Effects on Reactions of Tyrosine Phosphatases, Alvan C. Hengge and Z. Y. Zhang; ASBMB/DBC-ACS Joint Meeting, San Francisco, CA
1994
Isotope Effects on the Hydrolysis of Cobalt (II)- Bound Phosphate Esters, J. Rawlings, Alvan C. Hengge, and W. W. Cleland; American Society for Biochemistry and Molecular Biology Annual Meeting, Washington, D. C.
1993
Mechanistic Probes of Acyl and Phosphoryl Transfer Reactions Using Heavy Atom Isotope Effects, Alvan C. Hengge, R. A. Hess, A. E. Tobin, and W. W. Cleland; 13th Enzyme Mechanisms Conference, Key Largo, Florida
1992
Concertedness in Acyl Transfer Reactions of Esters, Alvan C. Hengge; 24th Reaction Mechanisms Conference, University of Maine, Orono, Maine
1991
Solution and Enzymatic Phosphoryl Transfer Reactions of Phosphodiesters: Characterization of Transition States by Heavy Atom Isotope Effects, Alvan C. Hengge and W. W. Cleland; Twelfth Enzyme Mechanisms Conference, San Diego, CA
1990
Determination of the Transition States for Phosphoryl Transfer and Hydrolysis Reactions, Alvan C. Hengge and W. W. Cleland; 23d Reaction Mechanisms Conference, University of Colorado-Boulder
Secondary Oxygen-18 Isotope Effects on Phosphodiester Hydrolysis Reactions, Alvan C. Hengge and W. W. Cleland; Gordon Research Conference on Isotopes in the Physical and Life Sciences, Oxnard, CA
1986
Oxidative Condensation Reactions Based Upon Triazolinedione Ylides, Alvan C. Hengge and R. M. Wilson; American Chemical Society 18th Central Regional Meeting, Bowling Green, Ohio
1905
Solution and Enzymatic Reactions of Phosphorothioate Monoesters: Thermodynamics and Mechanisms, I. E. Catrina and Alvan C. Hengge; 27th Reaction Mechanisms Conference, Pacific Grove, CA
Entropy Effects in the Catalytic Efficiencies of Phosphatases, R. H. Hoff and Alvan C. Hengge; 27th Reaction Mechanisms Conference, Pacific Grove, CA
The catalytic mechanism of purple acid phosphatases, N. Mitic, R. S. Cox, M. Lanznaster, L. R. Gahan, and A. Neves; ICBIC 13, Vienna, Austria