Synthesis and Antibacterial Activity Study of a Novel Class of Cationic Anthraquinone Analogs

Authors

Jianjun Zhang, Utah State University
Nathan Redman, Utah State University
Anthony Phillip Litke, Utah State UniversityFollow
Jia Zeng, Utah State University
Jixun Zhan, Utah State UniversityFollow
Ka-Yee Chan, Utah State University
Cheng-Wei Tom Chang, Utah State UniversityFollow

Document Type

Article

Journal/Book Title

Bioorganic & Medicinal Chemistry

Publication Date

1-1-2011

Publisher

Elsevier

Volume

19

Issue

1

First Page

498

Last Page

503

Abstract

An approach that combines solid phase and solution phase synthesis of oligosaccharides via the assistance of sonication has been developed. By employing the traceless linker, the designed oligosaccharides can be obtained in pure form and, more importantly, ready for incorporation to aglycons of interest via ‘Click’ chemistry or amide linkage. The overall strategy will facilitate the studies of roles of carbohydrates in bioactive compounds.

Comments

PubMed PMID: 21111625

Recommended Citation

Zhang, J.; Redman, N.; Litke, P.; Zeng, J.; Zhan, J.; Chan, K. Y.; Chang, C.-W. T. “Synthesis and Antibacterial Activity Study of a Novel Class of Cationic Anthraquinone Analogs.” Bioorg. Med. Chem. 2011, 19, 498-503. PubMed PMID: 21111625