A major effort has been made by the beef industry in recent years to reduce the economic loss from injection site lesions. Injections of almost any vaccine or medication causes some lesion. The extent, severity and economic loss of the resulting lesion can be greatly reduced with cleanliness and by use of careful techniques for the placement of product into specific, designated sites.
Bagley, Clell, "Realizing the Impact of Injection Site Lesions" (2001). All Current Publications. Paper 453.