Title

Neuropsychiatric Symptoms in Dementia Patients With and Without a History of Traumatic Brain Injury

Document Type

Article

Journal/Book Title/Conference

Journal of Neuropsychiatry and Clinical Neurosciences

Volume

22

Issue

2

Publisher

American Neuropsychiatric Association

Publication Date

2010

First Page

166

Last Page

172

DOI

10.1176/appi.neuropsych.22.2.166

Abstract

The authors aim to determine if a history of traumatic brain injury (TBI) assessed before dementia onset is associated with a higher risk of neuropsychiatric symptoms after dementia onset. A population-based incident series of people with dementia were assessed for TBI prior to onset of dementia and for neuropsychiatric symptoms after the onset, using the Neuropsychiatric Inventory. Participants with predementia TBI were more likely to exhibit disinhibition (12.7% versus 5.4%, OR=2.8, p=0.02), but not other neuropsychiatric symptoms. Traumatic brain injury may increase the risk of disinhibition in patients with dementia.