Psychology Faculty Publications Copyright (c) 2013 Utah State University All rights reserved. http://digitalcommons.usu.edu/psych_facpub Recent documents in Psychology Faculty Publications en-us Wed, 20 Mar 2013 01:36:16 PDT 3600 Dissociation of the role of the prelimbic cortex in interval timing and resource allocation: beneficial effect of norepinephrine and dopamine reuptake inhibitor nomifensine on anxiety-inducing distraction http://digitalcommons.usu.edu/psych_facpub/1055 http://digitalcommons.usu.edu/psych_facpub/1055 Mon, 18 Mar 2013 08:44:04 PDT Emotional distracters impair cognitive function. Emotional processing is dysregulated in affective disorders such as depression, phobias, schizophrenia, and PTSD. Among the processes impaired by emotional distracters, and whose dysregulation is documented in affective disorders, is the ability to time in the seconds-to-minutes range, i.e. interval timing. Presentation of task-irrelevant distracters during a timing task results in a delay in responding suggesting a failure to maintain subjective time in working memory, possibly due to attentional and working memory resources being diverted away from timing, as proposed by the Relative Time-Sharing model. We investigated the role of the prelimbic cortex in the detrimental effect of anxiety-inducing task-irrelevant distracters on the cognitive ability to keep track of time, using local infusions of norepinephrine and dopamine reuptake inhibitor nomifensine in a modified peak-interval procedure with neutral and anxiety-inducing distracters. Given that some antidepressants have beneficial effects on attention and working memory, e.g., decreasing emotional response to negative events, we hypothesized that nomifensine would improve maintenance of information in working memory in trials with distracters, resulting in a decrease of the disruptive effect of emotional events on the timekeeping abilities. Our results revealed a dissociation of the effects of nomifensine infusion in prelimbic cortex between interval timing and resource allocation, and between neutral and anxiety-inducing distraction. Nomifensine was effective only during trials with distracters, but not during trials without distracters. Nomifensine reduced the detrimental effect of the distracters only when the distracters were anxiety-inducing, but not when they were neutral. Results are discussed in relation to the brain circuits involved in Relative Time-Sharing of resources, and the pharmacological management of affective disorders.

]]> Alexander R. Matthews et al. Use of transient evoked otoacoustic emissions with school-aged children http://digitalcommons.usu.edu/psych_facpub/1053 http://digitalcommons.usu.edu/psych_facpub/1053 Mon, 24 Sep 2012 10:30:48 PDT N. B. Culpepper et al. Hörprüfungen für alle Neugeborenen auf der Grundlage oto-akustischer Emissionen? Ein Beitrag zur Frühdiagnose entwicklungsgefährdeter Kinder http://digitalcommons.usu.edu/psych_facpub/1054 http://digitalcommons.usu.edu/psych_facpub/1054 Mon, 24 Sep 2012 10:30:48 PDT Karl R. White Universal newborn hearing screening: Working toward a state plan http://digitalcommons.usu.edu/psych_facpub/1052 http://digitalcommons.usu.edu/psych_facpub/1052 Mon, 24 Sep 2012 10:30:47 PDT A. B. Maxon et al. The USA national consortium for universal hearing screening http://digitalcommons.usu.edu/psych_facpub/1050 http://digitalcommons.usu.edu/psych_facpub/1050 Mon, 24 Sep 2012 10:30:46 PDT Karl R. White Progress towards universal newborn hearing screening in the USA. The role of transient evoked otoacoustic emissions http://digitalcommons.usu.edu/psych_facpub/1051 http://digitalcommons.usu.edu/psych_facpub/1051 Mon, 24 Sep 2012 10:30:46 PDT Karl R. White Improving TEOAE newborn hearing screening techniques and procedures http://digitalcommons.usu.edu/psych_facpub/1049 http://digitalcommons.usu.edu/psych_facpub/1049 Mon, 24 Sep 2012 10:30:45 PDT Karl R. White Universal newborn hearing screening using TEOAEs http://digitalcommons.usu.edu/psych_facpub/1047 http://digitalcommons.usu.edu/psych_facpub/1047 Mon, 24 Sep 2012 10:30:44 PDT Karl R. White et al. The practicability of implementing TEOAE-based universal newborn hearing screening programs http://digitalcommons.usu.edu/psych_facpub/1048 http://digitalcommons.usu.edu/psych_facpub/1048 Mon, 24 Sep 2012 10:30:44 PDT Karl R. White Implementing TEOAE-based universal newborn hearing screening: The National Consortium for Universal Newborn Hearing Screening http://digitalcommons.usu.edu/psych_facpub/1046 http://digitalcommons.usu.edu/psych_facpub/1046 Mon, 24 Sep 2012 10:30:43 PDT Karl R. White Implementing newborn hearing screening: Why, when and how? http://digitalcommons.usu.edu/psych_facpub/1045 http://digitalcommons.usu.edu/psych_facpub/1045 Mon, 24 Sep 2012 10:30:42 PDT Karl R. White TEOAE-based universal newborn hearing screening http://digitalcommons.usu.edu/psych_facpub/1043 http://digitalcommons.usu.edu/psych_facpub/1043 Mon, 24 Sep 2012 10:30:41 PDT N. B. Culpepper et al. The NIH Consensus Conference Panel recommendation for universal newborn hearing screening: Foresight or folly http://digitalcommons.usu.edu/psych_facpub/1044 http://digitalcommons.usu.edu/psych_facpub/1044 Mon, 24 Sep 2012 10:30:41 PDT Karl R. White Why the implementation of universal newborn hearing screening in the USA is gathering momentum http://digitalcommons.usu.edu/psych_facpub/1042 http://digitalcommons.usu.edu/psych_facpub/1042 Mon, 24 Sep 2012 10:30:40 PDT Karl R. White Newborn hearing screening in the USA: Reality and myths http://digitalcommons.usu.edu/psych_facpub/1040 http://digitalcommons.usu.edu/psych_facpub/1040 Mon, 24 Sep 2012 10:30:39 PDT Karl R. White Universal newborn hearing screening using transient evoked otoacoustic emissions http://digitalcommons.usu.edu/psych_facpub/1041 http://digitalcommons.usu.edu/psych_facpub/1041 Mon, 24 Sep 2012 10:30:39 PDT Karl R. White Emerging challenges with newborn hearing screening http://digitalcommons.usu.edu/psych_facpub/1039 http://digitalcommons.usu.edu/psych_facpub/1039 Mon, 24 Sep 2012 10:30:38 PDT Karl R. White Guidelines for implementing universal newborn hearing screening programs http://digitalcommons.usu.edu/psych_facpub/1037 http://digitalcommons.usu.edu/psych_facpub/1037 Mon, 24 Sep 2012 10:30:37 PDT Karl R. White Statewide management of information from newborn hearing screening programs http://digitalcommons.usu.edu/psych_facpub/1038 http://digitalcommons.usu.edu/psych_facpub/1038 Mon, 24 Sep 2012 10:30:37 PDT Karl R. White Newborn hearing screening http://digitalcommons.usu.edu/psych_facpub/1036 http://digitalcommons.usu.edu/psych_facpub/1036 Mon, 24 Sep 2012 10:30:36 PDT M. Robinette et al.