Emerging Infectious Diseases
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus–viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection.
EID Rosenke K, Feldmann H, Westover JB, Hanley P, Martellaro C, Feldmann F, et al. Use of Favipiravir to Treat Lassa Virus Infection in Macaques. Emerg Infect Dis. 2018;24(9):1696-1699. https://dx.doi.org/10.3201/eid2409.180233