README supplementary file 3

Author(s) AND their Email addresses
James Pestka, pestka@msu.edu
Abby Benninghoff, abby.benninghoff@usu.edu

Title of Dataset:
Mapping of Dynamic Transcriptome Changes Associated with Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse.  Supplementary File 3 Ð nSolver significance scores. 

Description (short description of your dataset; indicate it is supporting an article):
Microsoft Excel document with output from nSolver for global and directed significance scores for immune pathways.  This data set is supporting material for a journal article.


Supplementary file 3 row definitions.
Significance score type
Type of score used, either global or directed
Experiment description
Indicates experiment to which the data belong.  See figure 1 in accompanying manuscript for experiment outlines.
Treatment comparison
Indicates the treatment comparisons made.  Note that some comparisons were not by treatment.
Tissue
Indicates the tissue sampled (lung, kidney or spleen)
Time point
Indicates time point at which the sample was obtained.  Note that some comparisons were made across time points (e.g., Lung.W13 vs Lung.W9)
The remaining rows show significance scores for each of the pathways as defined by the probe annotations (see Supplementary file 1).


Discipline: Toxicology

Keywords:
autoimmunity, NanoString, lung, systemic lupus erythematosus, silica, transcriptome

Journal:  data supports publication in journal Frontiers in Immunology


Volume, Issue, Date (year is fine that is all you have): 2019  (expected)
For journal issue


Embargo:  3 months embargo, or until journal article is published.
.