The phase changes calcium oxalate trihydrate-weddellite, weddellite-calcium oxalate monohydrate and calcium oxalate trihydrate-whewellite are individually examined at the atomic level from a theoretical point of view; concomitantly the topological requirements necessary for phase stability are clarified for each structure type. In solution a sequential series of phase transitions according to the steps calcium oxalate trihydrate-weddellite-whewellite is not likely to be energetically favoured; direct conversion of calcium oxalate trihydrate to whewellite should be, instead, ordinarily expected.
It is formally demonstrated that along two axial directions a set of atoms is in essentially identical positions in both weddellite and whewellite. This notwithstanding, it is concluded that epitactic catalysis cannot and should not be considered a common mechanism for the formation of whewellite from weddellite (and vice versa) or of kidney stones in general.
"Phase Transitions of Calcium Oxalate Trihydrate and Epitaxy in the Weddellite-Whewellite System,"
Scanning Electron Microscopy: Vol. 1986
, Article 45.
Available at: https://digitalcommons.usu.edu/electron/vol1986/iss4/45