Date of Award:

5-2012

Document Type:

Thesis

Degree Name:

Master of Science (MS)

Department:

Mechanical and Aerospace Engineering

Advisor/Chair:

Robert E. Spall

Abstract

There exist several different numerical models for predicting bubble coalescence and breakup using computational fluid dynamics (CFD). Various combinations of these models will be employed to model a bioreactor process in a stirred reactor tank. A mass transfer coefficient, Kla, has been calculated and compared to those found experimentally by Thermo-Fisher Scientific, to validate the accuracy of currently available mathematical models for population balance equations. These include various combinations of bubble breakup and coalescence models coupled with the calculation of mass transfer coefficients.

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Comments

This work made publicly available electronically on September 20, 2012.

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