Date of Award:


Document Type:


Degree Name:

Master of Science (MS)


Nutrition, Dietetics, and Food Sciences


Bonita W. Wyse


Information on human needs for pantothenic acid is limited and no recommended daily allowance has been established; although a safe and adequate level of 4-7 mg/day has been suggested for adults and adolescents. The adolescent population is often at risk for nutritional problems because of unusual eating patterns and major physiological changes which occur at this time. Pantothenic acid levels in urine, whole-blood and erythrocytes were determined in a healthy adolescent population using radioimmunoassay techniques. Dietary intakes were calculated from 4 day diet records and evaluated using a computer data base developed at Utah State University in conjunction with USDA.

Forty-nine percent of the females and 15 percent of the males consumed less than 4 mg/day; however average blood levels for both males and females were in a 11normal11 range relative to other populations {411.9 ± 102.8 ng/ml and 344.5 ± 113.6 ng/ml, respectively). Dietary intake was highly correlated to urinary excretion (p < 0.001). Levels of pantothenic acid in erythrocytes correlated well to dietary intake and urinary excretion. A model was developed to predict circulating levels of pantothenic acid from dietary intake and urinary excretion.