Date of Award:

5-1-1953

Document Type:

Thesis

Degree Name:

Master of Science (MS)

Department:

Biology

Department name when degree awarded

Physiology

Committee Chair(s)

Not Specified

Committee

Not Specified

Abstract

Damage to the germinal tissue of the ovary by radiation was reported in 1905 by Halberstaedter and by Bergonie and Tribondeau (2). These workers stated only that X-irradiation of the ovary injured the organ and resulted in a marked decrease in size. In 1913 Lacassagne (2) reported the effects of X-irradiation on the ovary of the rabbit. After intensive study he reported that the ovary might be made sterile for a time but that recovery could take place. Primitive ova not killed at the time of irradiation would develop, and the animal could give birth to living young. Since these early reports were published there has been much work on ovary irradiation using X-rays, radium salts, and more recently, as they have become available, isotopes produced by cyclotrons and atomic piles. Warren, et al. (12) reported that the most spectacular effect of irradiation with radioactive phosphorus on the ovary was the reduced size due to a reduction in number of Graafian follicle and the subsequent lack of corpora lutea.

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