Date of Award:

5-1-1952

Document Type:

Thesis

Degree Name:

Master of Science (MS)

Department:

Biology

Department name when degree awarded

Physiology

Committee Chair(s)

Not Specified

Committee

Not Specified

Abstract

The first account of radiation damage to male germinal tissue was published in 1903 by Albers-Schoenberg, and stated only that rabbits were made sterile by repeated exposure to X-ray irradiation. By 1925 numerous papers (Blanc, 1906; Barratt and Arnold, 1912; and Schinz and Slotopolsky, 1925) discussing the histological and cytological effects of irradiation on the testis had appeared. In 1928 Lacassagne, Lattes, and Fournier, using uranium x as an external source of beta radiation, reported damage to the testis of the same nature as that caused by X-ray irradiation (2). Within a few years internal irradiation of testis tissue was investigated. This was made possible by the injection of radium salts, and later, as they becane available from the atomic piles and cyclotrons, the various radioactive isotopes. It was then evident that the effects of alpha, beta, and gamma irradiation were qualitatively the same whether applied externally or internally, and only in extent and site of damage did the effects differ (2. 7).

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