Date of Award:
5-1-1981
Document Type:
Thesis
Degree Name:
Master of Science (MS)
Department:
Biology
Department name when degree awarded
Life Sciences:Biology
Committee Chair(s)
Rex S. Spendlove
Committee
Rex S. Spendlove
Committee
Nabil N. Youseff
Committee
Bill B. Barnett
Committee
Scott M. Clark
Abstract
The purpose of this study was to describe some of the ultrastructural events which occur in Madin-Darby bovine kidney cells infected with bovine rotavirus. Several observations were made in this study which have not been previously reported. First, distension of the rough endoplasmic reticulum cisternae was observed to occur before the entry of virus particles. Second, an increase in ribosome-like particles in the cytoplasm was seen to occur. Third, bundles of microfilaments were often seen near the nuclear envelope, mitochondria, and the rough endoplasmic reticulum. Fourth, two different densities of viroplasm were observed. Fifth, progeny virus particles were observed in distended portions of the nuclear envelope. Sixth, three filaments were seen to trail assembling progeny virus as they gained entry into the cisternae of the rough endoplasmic reticulum. Seventh, a five-point symmetry was observed in the center of assembling virions. Eighth, Virus particles were observed to become associated with the outer mitochondrial membrane, assemble and enter the mitochondria in a similar fashion to virus particles which assemble at the rough endoplasmic reticulum membranes. Ninth, another mode of progeny virus release was observed.
Recommended Citation
Mjaatvedt, Corey H., "Electron Microscopic Observation of the Development of a Bovine Rotavirus in Madin-Darby Bovine Kidney Cells" (1981). Biology. 474.
https://digitalcommons.usu.edu/etd_biology/474
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