Heavy ion microprobes (HIM) such as 3 MeV Si2+ and 3 MeV p2+ have been applied to the elemental analysis by PIXE (proton-induced X-ray emission). It was found that silicon and phosphorus microprobes have several times higher sensitivity for aluminum Kα X-rays than 2 MeV proton microprobes, and detection limits were more favorable in a phosphorus microprobe. Using a 3 MeV p2+ microprobe, the liver of a rat, which had been injected with aluminum-lactate, was investigated and it was found that aluminum segregates in areas with a dimension of about 10 μm. These areas could hardly be observed with 2 MeV proton microprobes.
Horino, Yuji; Mokuno, Yoshiaki; Kinomura, Atsushi; Fujii, Kanenaga; and Yumoto, Sakae
"Micro-PIXE (Particle Induced X-Ray Emission) Analysis of Aluminum in Rat-Liver Using MeV Heavy Ion Microprobes,"
Scanning Microscopy: Vol. 7
, Article 10.
Available at: https://digitalcommons.usu.edu/microscopy/vol7/iss4/10