Document Type

Article

Journal/Book Title/Conference

Prostaglandins Leukotrienes and Essential Fatty Acids

Volume

111

Publisher

Churchill Livingstone

Publication Date

2-17-2016

First Page

37

Last Page

44

DOI

10.1016/j.plefa.2016.03.003

Abstract

The goal of this study was to evaluate the role of both the % of dietary, 18-carbon PUFA (2.5%, 5% and 10%) and the n-6:n-3 ratio (1:1, 10:1 and 20:1) on the acute inflammatory response. Mice were fed diets for 8 weeks and injected intraperitoneally with LPS to induce acute inflammation. After 24. h mice were sacrificed and plasma cytokines measured. Diets significantly affected the erythrocyte PUFA composition and the effect of PUFA ratio was more prominent than of PUFA concentration. The % dietary PUFA affected feed efficiency (p

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Biochemistry Commons

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