Location
Salt Lake Community College
Start Date
5-10-2004 9:00 AM
Description
Biosensors exploit the theoretical and instrumental approaches of analytical chemistry and the unique properties of biological molecules. They utilize the intermolecular interactions and specificity found in systems such as hormone-receptor, antigenantibody, pathogen-host and substrate-enzyme. Manipulation of the structural and energetic factors that guide formation of these macromolecular complexes may provide a rational basis for the development of new sensor technology. To this end we have investigated myoglobin thin films for their ability to bind ligands. FTIR spectroscopy has been chosen as the transduction methods and has been shown to discriminate between several analytes.
An Infrared Approach to Thin-Layer Based Biosensors
Salt Lake Community College
Biosensors exploit the theoretical and instrumental approaches of analytical chemistry and the unique properties of biological molecules. They utilize the intermolecular interactions and specificity found in systems such as hormone-receptor, antigenantibody, pathogen-host and substrate-enzyme. Manipulation of the structural and energetic factors that guide formation of these macromolecular complexes may provide a rational basis for the development of new sensor technology. To this end we have investigated myoglobin thin films for their ability to bind ligands. FTIR spectroscopy has been chosen as the transduction methods and has been shown to discriminate between several analytes.