Early Post-Radiation Changes of Red Blood Cell Shape in Rats

Authors

V. D. Zharskaya, "Primorsky" Health Rehabilitation Center
A. B. Chukhlovin, Petrov Research Institute of OncologyFollow

Abstract

Scanning electron microscopy (SEM) of red blood cells in whole blood samples from rats was performed following acute γ-irradiation of animals with 0.25 to 1 Gy. Increased incidence of echinocytosis was observed and found to be dose- and time-dependent. At a higher radiation dose (1 Gy), echinocytosis was revealed within 5 minutes after treatment and persisted up to 3 weeks. The data demonstrate the applicability of SEM for detecting minimal radiation-induced lesions of red blood cells.

Recommended Citation

Zharskaya, V. D. and Chukhlovin, A. B. (1996) "Early Post-Radiation Changes of Red Blood Cell Shape in Rats," Scanning Microscopy: Vol. 10: No. 1, Article 22.
Available at: https://digitalcommons.usu.edu/microscopy/vol10/iss1/22