The Nucleation and Growth of Calcium Oxalate Monohydrate on Self-Assembled Monolayers (SAMs)

Authors

Allison A. Campbell, Battelle Pacific Northwest Laboratory
Glen E. Fryxell, Battelle Pacific Northwest Laboratory
Gordon L. Graff, Battelle Pacific Northwest Laboratory
Peter C. Rieke, Battelle Pacific Northwest Laboratory
Barbara J. Tarasevich, Battelle Pacific Northwest Laboratory

Abstract

A physical chemical approach was used to study calcium oxalate monohydrate (COM) nucleation and growth on various organic interfaces. Self-assembling monolayers (SAMs), containing derivatized organic functional groups, were designed to mimic various amino acid residues present in both urine and stone matrix macromolecules. Derivatized surfaces include SAMs with terminal methyl, bromo, imidazole, and thiazolidine-carboxylic acid functional groups. Pronounced differences in COM deposition were observed for the various interfaces with the imidazole and thiazolidine surfaces having the greatest effect and the methyl and bromo groups having little or no nucleating potential.

Recommended Citation

Campbell, Allison A.; Fryxell, Glen E.; Graff, Gordon L.; Rieke, Peter C.; and Tarasevich, Barbara J. (1992) "The Nucleation and Growth of Calcium Oxalate Monohydrate on Self-Assembled Monolayers (SAMs)," Scanning Microscopy: Vol. 7: No. 1, Article 46.
Available at: https://digitalcommons.usu.edu/microscopy/vol7/iss1/46