Date of Award:
5-1966
Document Type:
Thesis
Degree Name:
Master of Science (MS)
Department:
Plants, Soils, and Climate
Department name when degree awarded
Plant Nutrition and Biochemistry
Committee Chair(s)
George W. Cochran
Committee
George W. Cochran
Committee
Harris Van Orden
Committee
Orson Cannon
Committee
Amrik S. Dhaliwal
Abstract
Research on biosynthesis of tobacco mosaic virus (TMV) ribonucleic acid (RNA) in vitro has been reported by Cochran, et al; Karasek and Schramm; Kim and Wildman; Cornuet and Astier; and Tongur and Baland in. It has been postulated that the replication of a number of viruses containing single-stranded RNA is accompanied by the formation of a virus-specific double-stranded helical RNA, the replicative form. This has been demonstrated both for animal and bacterial viruses including MS2. The double helical structure of purified replicative form of MS2 was established by X-ray diffraction studies. One of the strands was shown to be a viral RNA strand of the parental type ("plus" strand), the other being complementary to it ("minus" strand). Studies on Escherichia coli infected with RNA phages suggest that a structure containing both a "plus 11 and a "minus " strand is an obligatory intermediate in viral reproduction.
Checksum
4a1883b9a1f84134e2b38f03b5f4e8d5
Recommended Citation
Fok, Agnes P., "A Study of the Factors Influencing the Synthesis of Tobacco Mosaic Viral RNA in a Partially Purified Synthesizing System" (1966). All Graduate Theses and Dissertations, Spring 1920 to Summer 2023. 3827.
https://digitalcommons.usu.edu/etd/3827
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