Date of Award:
5-2016
Document Type:
Dissertation
Degree Name:
Doctor of Philosophy (PhD)
Department:
Chemistry and Biochemistry
Committee Chair(s)
Lisa M. Berreau
Committee
Lisa M. Berreau
Committee
Alvan C. Hengge
Committee
Cheng-Wei T. Chang
Committee
David Hole
Committee
Yujie Sun
Abstract
The research presented in this dissertation focuses on the oxidative cleavage of chemical bonds between two carbon atoms. This type of reactivity is of significant interest due to its potential application toward the development of ways to convert chemical feed stock into useful products such as pharmaceuticals, polymers and fuels in an environmentally benign and cost-efficient manner. Reactions that cleave specific carbon-carbon bonds, are catalyzed by earth-abundant metals, and involve O2 as the terminal oxidant, are of particular interest.
Our strategy has been to study the oxidative carbon-carbon bond cleavage reactivity of metal complexes containing components similar to structures found nature. The results presented herein demonstrate that such reactions are highly sensitive to the nature of the metal/organic combination undergoing reaction, and that subtle factors can dramatically influence the rate of such reactions. Outcomes of the research include the discovery of a way to modulate the reactivity of potential anti-cancer compounds and insight into how Cu(II) centers can be tuned for O2 reactivity.
Checksum
4b4e0077002282a3425fe9d3b77572bc
Recommended Citation
Saraf, Sushma L., "Oxidative Carbon-Carbon Bond Cleavage Reactions of Metal Flavonolato and Chlorodiketonate Complexes" (2016). All Graduate Theses and Dissertations, Spring 1920 to Summer 2023. 5161.
https://digitalcommons.usu.edu/etd/5161
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