Date of Award:

5-2016

Document Type:

Dissertation

Degree Name:

Doctor of Philosophy (PhD)

Department:

Chemistry and Biochemistry

Committee Chair(s)

Steve Scheiner

Committee

Steve Scheiner

Committee

Alexander I. Boldyrev

Committee

Alvan Hengge

Committee

T. C. Shen

Committee

Cheng-Wei Tom Chang

Abstract

Known to be weaker than conventional covalent bonds, non-covalent bonds, especially hydrogen bond, has shown to be of great importance in molecular structures such as DNA, RNA, proteins and other organic frameworks. In this dissertation, we looked at non-covalent interactions other than the hydrogen bond. Replacement of the bridging hydrogen atom in a typical hydrogen bond by other atoms such a halogen, chalcogen and tetrel lead to the formation of interactions which are comparable in strength to the hydrogen bond. Unlike the hydrogen bond which arises mainly from electrostatics, these unconventional interactions mostly result from induction. Besides studying the fundamentals of these interactions, potential applications of these forces especially in organic catalysis are also explored.

Checksum

8c42c2bdbed2e45704e83dbff2a762e0

Included in

Chemistry Commons

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