Title

Mutants of Metarhizium anisopliae with increase[d] virulence toward mosquito larvae

Document Type

Article

Journal/Book Title/Conference

Canadian Journal of Genetics and Cytology

Volume

20

Issue

2

Publication Date

6-1-1978

First Page

211

Last Page

219

DOI

10.1139/g78-024

Abstract

A wild-type strain of Metarhizium anisopliae (Metsch.) Sorokin, an imperfect fungus, killed 76% of Culex pipiens pipiens larvae within five days after spore administration. A spontaneous mutant strain was selected whose LD50 was less than half that of the wild type, and whose LT50 was one day faster. This mutant also showed early, dense sporulation, rapid in vitro spore germination, and enhanced production of destruxins. It is probable that at least one of these additional characteristics is related to the mutation to hypervirulence.

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