Biological Reviews Cambridge Philosophical Society
Identifying patterns and drivers of infectious disease dynamics across multiple scales is a fundamental challenge for modern science. There is growing awareness that it is necessary to incorporate multi-host and/or multi-parasite interactions to understand and predict current and future disease threats better, and new tools are needed to help address this task. Eco-phylogenetics (phylogenetic community ecology) provides one avenue for exploring multi-host multi-parasite systems, yet the incorporation of eco-phylogenetic concepts and methods into studies of host pathogen dynamics has lagged behind. Eco-phylogenetics is a transformative approach that uses evolutionary history to infer present-day dynamics. Here, we present an eco-phylogenetic framework to reveal insights into parasite communities and infectious disease dynamics across spatial and temporal scales. We illustrate how eco-phylogenetic methods can help untangle the mechanisms of host-parasite dynamics from individual (e.g. co-infection) to landscape scales (e.g. parasite/host community structure). An improved ecological understanding of multi-host and multi-pathogen dynamics across scales will increase our ability to predict disease threats.
Fountain-Jones, Nicholas M.; Pearse, William D.; Escobar, Luis E.; Alba-Casals, Ana; Carver, Scott; Davies, T. Jonathan; Kraberger, Simona; Papes, Monica; Vandegrift, Kurt; Worsley-Tonks, Katherine; and Craft, Meggan E., "Towards an Eco-phylogenetic Framework for Infectious Disease Ecology" (2017). Biology Faculty Publications. Paper 1573.