Date of Award:
Doctor of Philosophy (PhD)
Randolph V. Lewis (Committee Co-Chair), Ronald C. Sims (Committee Co-Chair)
Randolph V. Lewis
Ronald C. Sims
David W. Britt
Justin A. Jones
Spider silks are incredible natural materials that possess desirable combinations of strength, elasticity, weight, and robustness. Other properties such as biocompatibility and biodegradability further increase the worth of these materials. The possibility of farming spiders is impractical due to spiders’ natural behaviors. Modern biotechnologies have allowed for recombinant spider silk proteins (rSSps) to be produced without the use of spiders. However, the features responsible for spider silks impressive properties can cause difficulties with producing silk materials. A recently developed water-based and biomimetic solvation method has provided a solution to such difficulties and has also led to novel silk biomaterials. Most notable among these materials are; coatings, fibers, adhesives, films, foams, hydrogels, aerogels, capsules, and sponges. Many of these material possess specific properties that may be suitable for many commercial, industrial, and biomedical uses. This study has developed numerous spider silk biomaterials, identified their essential properties and features, provided preliminary evidence for various applications, and identified directions for future studies and uses.
Harris, Thomas I., "Development and Characterization of Aqueous-Based Recombinant Spider Silk Protein Biomaterials with Investigations into Potential Applications" (2018). All Graduate Theses and Dissertations, Spring 1920 to Summer 2023. 7251.
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