Class
Article
College
College of Science
Faculty Mentor
Steve Scheiner
Presentation Type
Oral Presentation
Abstract
The intramolecular bonding within proteins is of paramount importance to understand protein structure, folding, and stability with a direct impact on the accuracy of molecular modeling software. Hydrogen bonds are very common between amino acids and the most common of these is the N-H---O bond. It is not, however, the only type of hydrogen bond. Recent studies have suggested that N-H---N bonds exist and shouldn't be ignored. To investigate this, a comprehensive study of the ability of amino acids to form N-H---N bonds was performed via quantum chemical calculations. This presentation will discuss the results.
Location
Room 154
Start Date
4-12-2018 9:00 AM
End Date
4-12-2018 10:15 AM
N-H---N Hydrogen Bonds in Proteins
Room 154
The intramolecular bonding within proteins is of paramount importance to understand protein structure, folding, and stability with a direct impact on the accuracy of molecular modeling software. Hydrogen bonds are very common between amino acids and the most common of these is the N-H---O bond. It is not, however, the only type of hydrogen bond. Recent studies have suggested that N-H---N bonds exist and shouldn't be ignored. To investigate this, a comprehensive study of the ability of amino acids to form N-H---N bonds was performed via quantum chemical calculations. This presentation will discuss the results.