Session

session3

Location

Space Dynamics Laboratory, Auditorium Rm C

Start Date

5-9-2022 9:25 AM

End Date

5-9-2022 9:35 AM

Description

The brain is arguably the most important and complex component of any crewed mission. New technological developments must be made to gauge the damage of space to the brain, especially in complex and long-term missions. While it is understood that microgravity and radiation cause changes in the brain of astronauts, the nature and effects of these changes are largely unknown. To aid in elucidating these effects, we conducted experiments using a rotary cell culture system (RCCS) and are working actively with NASA to implement a chronic low-dose gamma radiation system. Initial trends in the effects of microgravity on brain organoids show an increase in cell death markers, a decrease in total size, and a reduction in the number of organized structures.

Available for download on Tuesday, May 09, 2023

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May 9th, 9:25 AM May 9th, 9:35 AM

Investigating the Effects of Radiation and Microgravity on Human Brain Organoids

Space Dynamics Laboratory, Auditorium Rm C

The brain is arguably the most important and complex component of any crewed mission. New technological developments must be made to gauge the damage of space to the brain, especially in complex and long-term missions. While it is understood that microgravity and radiation cause changes in the brain of astronauts, the nature and effects of these changes are largely unknown. To aid in elucidating these effects, we conducted experiments using a rotary cell culture system (RCCS) and are working actively with NASA to implement a chronic low-dose gamma radiation system. Initial trends in the effects of microgravity on brain organoids show an increase in cell death markers, a decrease in total size, and a reduction in the number of organized structures.