A Simple Sonication Method for Generating Monodispersed Nanoparticles of Hydrophobic Antioxidants

Brigham Young University Engineering Building, Provo, UT

Various hydrophobic antioxidants remain unexplored for the treatment of space radiation and oxidative stress due to their inability to enter the cell without a drug delivery vehicle as their surface properties cause them to suffer from a poor solubility. In this paper you will find a recent breakthrough of a new method to create neat antioxidant nanoparticles free of any surfactant whatsoever vastly improving inherent solubility. These nanoparticles are synthesized monodispersed with a low polydispersity. This is even more suitable for astronauts then other generation methods, as the cocktail is without any solvent or surfactant which can have unknown effects on the body in space conditions. This research paves the way for new antioxidants to be used to protect astronauts from diseases caused by space conditions such as radiation and microgravity.