A Population Study of Alzheimer's Disease: Findings From the Cache County Study on Memory, Health, and Aging

Document Type

Article

Journal/Book Title/Conference

Care Management Journals

Volume

6

Issue

2

Publisher

Springer Publishing Company

Publication Date

2005

First Page

107

Last Page

114

Abstract

There are several population-based studies of aging, memory, and dementia being conducted worldwide. Of these, the Cache County Study on Memory, Health and Aging is noteworthy for its large number of "oldest-old" members. This study, which has been following an initial cohort of 5,092 seniors since 1995, has reported among its major findings the role of the Apolipoprotein E gene on modifying the risk for Alzheimer's disease (AD) in males and females and identifying pharmacologic compounds that may act to reduce AD risk. This article summarizes the major findings of the Cache County study to date, describes ongoing investigations, and reports preliminary analyses on the outcome of the oldest-old in this population, the subgroup of participants who were over age 84 at the study's inception.

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