Antiviral Activity of Nucleoside Analogues Against SARS-Coronavirus (SARS-CoV)

Authors

Chung K. Chu, University of GeorgiaFollow
Srinivas Gadthula, University of Georgia
Xin Chen, University of Georgia
Hyunah Choo, University of Georgia
Sureyya Olgen, University of Georgia
Dale L. Barnard, Utah State UniversityFollow
Robert W. Sidwell, Utah State University

Document Type

Article

Journal/Book Title/Conference

Antiviral Chemistry and Chemotherapy

Volume

17

Issue

5

Publisher

International Medical Press

Publication Date

10-2006

First Page

285

Last Page

289

Abstract

The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.

Comments

Originally published by International Medical Press. Publisher's PDF available through remote link.

Recommended Citation

Chu, C.K., Gadthula, S., Chen, X., Choo, H., Olgen, S., Sidwell, R.W. and Barnard, D.L 2006. Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV). Antiviral Chemistry and Chemotherapy, 17: 285-289.