Title

Preparative isolation of destruxins from Metarhizium anisopliae by high performance liquid chromatography

Document Type

Article

Journal/Book Title/Conference

Journal of Liquid Chromatography

Volume

12

Issue

3

Publication Date

1-1-1989

First Page

383

Last Page

395

DOI

10.1080/01483918908051742

Abstract

A method has been developed for preparative isolation of destruxins, a group of major insecticidal cyclodepsipeptides from culture broth of Metarhizium anisopliae. Prepurification of the crude extract by flash chromatography on silica gel followed by HPLC on reverse phase C18 Column using linear gradients of acetonitrile-water permitted the isolation of ten destruxins.

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