Development of a Process for the Spinning of Synthetic Spider Silk
Document Type
Article
Journal/Book Title/Conference
ACS Biomaterials Science and Engineering
Volume
1
Issue
7
Publisher
American Chemical Society
Publication Date
6-5-2015
First Page
577
Last Page
584
Abstract
Spider silks have unique mechanical properties but current efforts to duplicate those properties with recombinant proteins have been unsuccessful. This study was designed to develop a single process to spin fibers with excellent and consistent mechanical properties. As-spun fibers produced were brittle, but by stretching the fibers the mechanical properties were greatly improved. A water-dip or water-stretch further increased the strength and elongation of the synthetic spider silk fibers. Given the promising results of the water stretch, a mechanical double-stretch system was developed. Both a methanol/water mixture and an isopropanol/water mixture were independently used to stretch the fibers with this system. It was found that the methanol mixture produced fibers with high tensile strength while the isopropanol mixture produced fibers with high elongation.
Recommended Citation
(2015) Cameron G. Copeland, Brianne E. Bell, Chad D. Christensen, and Randolph V. Lewis, Development of a Process for the Spinning of Synthetic Spider Silk ACS Biomaterials Science and Engineering 1 (7): 577–584 DOI: 10.1021/acsbiomaterials.5b00092