A convenient synthesis of phosphonothioic acids
Document Type
Article
Journal/Book Title
Tetrahedron
Publication Date
2003
Volume
59
Issue
5
First Page
595
Last Page
599
Abstract
A method for the convenient synthesis of phosphonothioates, or phosphonothioic acids, is reported. A significant advantage of the method is the alleviation of the need for purification of intermediates, other than washing with water. No chromatography is needed and the only purification step is the crystallization of the final product. The method uses standard reagents and should be applicable to the synthesis of phosphonothioic acids bearing a range of functional groups.
Recommended Citation
K. Swierczek, J. Peters and A. C. Hengge “A convenient synthesis of phosphonothioic acids.” Tetrahedron, 2003, 59/5, 595 – 599.
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