Phosphoryl Transfer Reactions
Document Type
Contribution to Book
Journal/Book Title
Encyclopedia of Life Sciences
Publication Date
2004
Publisher
Nature Publishing Group
Abstract
Phosphoryl transfer is the name given to the chemical process of the transfer of the phosphoryl group (PO3) from a phosphate ester or anhydride to a nucleophile. Nucleophilic attack by water on a phosphate monoester gives the hydrolysis product inorganic phosphate. This net dephosphorylation reaction is the process catalysed by phosphatases. The formation of phosphate esters is termed phosphorylation, and is accomplished in biological systems by kinases.
Recommended Citation
“Phosphoryl Transfer Reactions,” Alvan C. Hengge. In: Encyclopedia of Life Sciences. London: Nature Publishing Group. [doi: 10.1038/npg.els.0000608] http://www.els.net/
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