Chemical Synthesis of N-Aryl Glycosides

Authors

Marina Y. Fosso, Utah State University
Vincent P. N. Nziko, Utah State University
Cheng-Wei Tom Chang, Utah State UniversityFollow

Document Type

Article

Journal/Book Title

Journal of Carbohydrate Chemistry

Publication Date

10-31-2012

Publisher

Taylor & Francis

Volume

31

Issue

8

First Page

603

Last Page

619

Abstract

Along with the O- and C-aryl glycosides, N-aryl glycosides represent an important class of carbohydrate and heterocyclic aryl conjugates that possess diverse applications and implications of biological interest. However, most of the synthetic efforts have been directed toward the preparation of O- and C-aryl glycosides. This review focuses on the various strategies that have been employed to synthesize N-aryl glycosides, most of which developed in the past 20 years. Besides having their unique applications, these N-aryl glycosides can also be treated as the analogs of O- and C-aryl glycosides. Wide ranges of reaction conditions are discussed for the optimum conditions.

Recommended Citation

Fosso, M. Y.; Nziko, V. P. N.; Chang, C.-W. T. "Chemical Synthesis of N-Aryl Glycosides." J. Carbohydr. Chem. 2012, 31, 603-619.