Chemical Synthesis of N-Aryl Glycosides
Journal of Carbohydrate Chemistry
Taylor & Francis
Along with the O- and C-aryl glycosides, N-aryl glycosides represent an important class of carbohydrate and heterocyclic aryl conjugates that possess diverse applications and implications of biological interest. However, most of the synthetic efforts have been directed toward the preparation of O- and C-aryl glycosides. This review focuses on the various strategies that have been employed to synthesize N-aryl glycosides, most of which developed in the past 20 years. Besides having their unique applications, these N-aryl glycosides can also be treated as the analogs of O- and C-aryl glycosides. Wide ranges of reaction conditions are discussed for the optimum conditions.
Fosso, M. Y.; Nziko, V. P. N.; Chang, C.-W. T. "Chemical Synthesis of N-Aryl Glycosides." J. Carbohydr. Chem. 2012, 31, 603-619.