Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent
Document Type
Article
Journal/Book Title
Tetrahedron Letters
Publication Date
3-5-2014
Publisher
Elsevier
Volume
55
Issue
10
First Page
1839
Last Page
1842
Abstract
Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.
Recommended Citation
Zhang, Q.; Shrestha, J. P.; Chang, C.-W. T. "Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent." Tetrahedron Lett. 2014, 55, 1839-1842.
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