Anthropogenic and Natural Stressors and Their Effect on Immunity, Reproduction, and the Stress Response
Date of Award:
Doctor of Philosophy (PhD)
Susannah S. French
Susannah S. French
Edmund D. Brodie Jr.
Animals must be able to cope with many natural and human-made stressors in order to successfully survive and reproduce. These stressors can come in many forms and are increasing as human activities become more and more prevalent across the globe. In order to cope with these stressors, organisms must allocate limited energy away from processes such as reproduction to mount a stress response. This stress response involves the activation of the hypothalamic-pituitary-adrenal axis and results in a cascade of hormones and down-stream effects, such as changes in reproduction and immune function. In order to understand how reptiles and amphibians cope with a variety of stressors, I conducted seven experiments. I first validated an immune assay which can be employed across vertebrate taxa and can measure functional immune responses. I then analyzed effects of natural stressors (wounding, predator attacks, natural toxins, and food restriction) and/or human-made stressors (restraint and the anthropogenic toxins polybrominated diphenyl ether and indoxacarb) on reptiles and/or amphibians. In measuring many different stressors and several different animals (the side blotchedlizard, Uta stansburiana, the rough-skinned newt, Taricha granulosa, the wandering gartersnake, Thamnophis elegans, and the common gartersnake, T. sirtalis), I hoped to determine if patterns in energy allocation and trade-offs existed on a broad scale. I found that while there are some similarities among the responses, each organism exposed to different stressors had to be examined separately. This supports the emerging consensus that the stress response is extremely context-dependent and responses seen in one context cannot be inferred to other animals with different life-histories, sexes, geographic range, or previous experience. Because of this, researchers must focus on the population in question to assess physiological questions before making management decisions.
Neuman-Lee, Lorin A., "Anthropogenic and Natural Stressors and Their Effect on Immunity, Reproduction, and the Stress Response" (2016). All Graduate Theses and Dissertations. 4884.
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