Date of Award
1976
Degree Type
Report
Degree Name
Master of Science (MS)
Department
Mathematics and Statistics
Committee Chair(s)
Donald V. Sisson
Committee
Donald V. Sisson
Committee
Rex L. Hurst
Committee
Frederick J. Post
Abstract
Biological assays are essentially biological experiments. To compare the potencies of treatments on an agreed scale is generally of more interest than to compare the magnitude of effects of different treatments.
The relative potency, R = a/b, is defined as the ratio of the means of two equally effective doses where a is the mean of A and bis the mean of B. It is an estimate of the potency of one preparation, A, relative to that of the other, B.
Different procedures have been proposed to obtain the values of R and its confidence interval. Three of the these methods are compared and discussed here. They utilize the coefficient of variation, Fieller's theorem, and logarithms.
Recommended Citation
Lung, Catherine H., "An Empirical Comparison of Confidence Interval for Relative Potency" (1976). All Graduate Plan B and other Reports, Spring 1920 to Spring 2023. 1183.
https://digitalcommons.usu.edu/gradreports/1183
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