Date of Award
Animal, Dairy, and Veterinary Sciences
In an ongoing research project, the Center for Persons with Disabilities at Utah State University, in collaboration with Dr. Susan E. Swedo at the National Institute of Mental Health, is evaluating genetic factors affecting the development of PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections). PANDAS is manifested in a group of prepubertal children who develop obsessive-compulsive disorder (OCD) following infection with Group A beta-hemolytic Streptococcal (GABHS) bacteria. We are assessing single nucleotide polymorphisms (SNPs) in the promoter region of tumor necrosis factor (TNF)-α and other cytokines known to be important in autoimmune diseases.
VonNiederhausern, Corinna Wilhelmina, "Single Nucleotide Polymorphism (SNP) Analysis of Tumor Necrosis Factor (TNF)-α in Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Subjects" (2003). Undergraduate Honors Capstone Projects. 854.
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Anthony R. Torres
Departmental Honors Advisor
Stanly D. Illa