Timing of response differentiation in human motor cortex during a speeded Go/No-go task

Document Type

Article

Journal/Book Title/Conference

Neuroscience Research

Volume

85

Publisher

Elsevier

Publication Date

8-1-2014

First Page

65

Last Page

68

Abstract

We explored the brain's ability to quickly prevent a pre-potent but unwanted motor response. To address this, transcranial magnetic stimulation was delivered over the motor cortex (hand representation) to probe excitability changes immediately after somatosensory cues prompted subjects to either move as fast as possible or withhold movement. Our results showed a difference in motor cortical excitability 90 ms post-stimulus contingent on cues to either promote or prevent movement. We suggest that our study design emphasizing response speed coupled with well-defined early probes allowed us to extend upon similar past investigations into the timing of response inhibition.

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