Document Type
Article
Journal/Book Title/Conference
Prostaglandins Leukotrienes and Essential Fatty Acids
Volume
111
Publisher
Churchill Livingstone
Publication Date
2-17-2016
First Page
37
Last Page
44
Abstract
The goal of this study was to evaluate the role of both the % of dietary, 18-carbon PUFA (2.5%, 5% and 10%) and the n-6:n-3 ratio (1:1, 10:1 and 20:1) on the acute inflammatory response. Mice were fed diets for 8 weeks and injected intraperitoneally with LPS to induce acute inflammation. After 24. h mice were sacrificed and plasma cytokines measured. Diets significantly affected the erythrocyte PUFA composition and the effect of PUFA ratio was more prominent than of PUFA concentration. The % dietary PUFA affected feed efficiency (p
Recommended Citation
Hintze, K.J., Tawzer, J., Ward, R.E. Concentration and ratio of essential fatty acids influences the inflammatory response in lipopolysaccharide challenged mice (2016) Prostaglandins Leukotrienes and Essential Fatty Acids, . Article in Press. https://www.scopus.com/inward/record.url?eid=2-s2.0-84962163526&partnerID=40&md5=fa980c3c7d6625c6f7508e7196e50850