All Physics Faculty Publications

Photoacoustic Studies of Carboxymyoglobin

Document Type

Article

Journal/Book Title/Conference

Biophysical Journal

Volume

57

Publication Date

1990

First Page

229a

Last Page

229a

Abstract

Pulsed-laser photoacoustics offers a means for measuring the Fe-CO bond strength in carboxymyoglobin, as well as the dynamics of the protein following cleavage of the Fe-CO bond. Two groups have studied the problem in the past, with conflicting results [Leung et al., Chem. Phys. Letts. 141, 220 (1987); Westrick et al., Biochemistry 26, 8313 (1987)]. Preliminary results from our laboratory support a positve value for the enthalpy of formation of the Fe:CO geminate pair, formed within 10 nsec of photolysis of carboxymyoglobin. Data will be presented on the Fe-CO bond energy, and the volumetric and enthalpic changes which occur in myoglobin following Fe-CO bond cleavage.

Comments

Abstract from Biophysical Journal and is freely available through link. Abstracts are from the Thirty-Fourth Annual Meeting February 18–22, 1990 Baltimore Convention Center Baltimore, Maryland.

https://doi.org/10.1016/S0006-3495(90)82546-7

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