Class
Article
College
College of Agriculture and Applied Sciences
Department
Nutrition, Dietetics, and Food Sciences Department
Faculty Mentor
Robert Ward
Presentation Type
Poster Presentation
Abstract
Dietary fiber has a large impact on the microbiota composition and metabolic activity via the provision of fermentable substrates, yet, to date, there has been very little attention paid to modeling the fiber composition of rodent diets to that of humans. We propose to use nutrient density, a form of allometric scaling, to formulate metabolically stressful diets with fiber intake levels at the US average (50% AI), the IOM recommended level (100% AI), and a higher level (150% AI). The primary endpoint we focus on in this study is oral glucose tolerance, as high-fiber diets have been shown to prevent insulin resistance and type 2 diabetes (T2D) development in humans. The results will guide more focused rodent studies and human clinical studies designed to validate fiber profiles that improve health.
Location
Logan, UT
Start Date
4-12-2023 1:30 PM
End Date
4-12-2023 2:30 PM
Included in
Does Fiber Reduce Weight Gain and Improve Metabolism?
Logan, UT
Dietary fiber has a large impact on the microbiota composition and metabolic activity via the provision of fermentable substrates, yet, to date, there has been very little attention paid to modeling the fiber composition of rodent diets to that of humans. We propose to use nutrient density, a form of allometric scaling, to formulate metabolically stressful diets with fiber intake levels at the US average (50% AI), the IOM recommended level (100% AI), and a higher level (150% AI). The primary endpoint we focus on in this study is oral glucose tolerance, as high-fiber diets have been shown to prevent insulin resistance and type 2 diabetes (T2D) development in humans. The results will guide more focused rodent studies and human clinical studies designed to validate fiber profiles that improve health.