Presenter Information

Class

Article

College

College of Engineering

Department

Biological Engineering Department

Faculty Mentor

David Britt

Presentation Type

Poster Presentation

Abstract

The current treatment to Cytomegalovirus, ganciclovir, kills neutrophils, a type of cell in the immune system. In an effort to reduce the concentration of ganciclovir, quercetin and poloxamer 188 have been added in treatment in a cellular and mouse model. This treatment has been successful, but can be further optimized by reworking the ratio of quercetin to poloxamer 188 and by adding vitamin c to prevent oxidation.

Location

Logan, UT

Start Date

4-12-2023 12:30 PM

End Date

4-12-2023 1:30 PM

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Apr 12th, 12:30 PM Apr 12th, 1:30 PM

Optimizing Treatment of Cytomegalovirus

Logan, UT

The current treatment to Cytomegalovirus, ganciclovir, kills neutrophils, a type of cell in the immune system. In an effort to reduce the concentration of ganciclovir, quercetin and poloxamer 188 have been added in treatment in a cellular and mouse model. This treatment has been successful, but can be further optimized by reworking the ratio of quercetin to poloxamer 188 and by adding vitamin c to prevent oxidation.