Presenter Information

Alisa Dabb, Utah State University

Class

Article

College

College of Engineering

Department

Biological Engineering Department

Faculty Mentor

David Britt

Presentation Type

Poster Presentation

Abstract

The current treatment to Cytomegalovirus, ganciclovir, kills neutrophils, a type of cell in the immune system. In an effort to reduce the concentration of ganciclovir, quercetin and poloxamer 188 have been added in treatment in a cellular and mouse model. This treatment has been successful, but can be further optimized by reworking the ratio of quercetin to poloxamer 188 and by adding vitamin c to prevent oxidation.

Location

Logan, UT

Start Date

4-12-2023 12:30 PM

End Date

4-12-2023 1:30 PM

Share

COinS
 
Apr 12th, 12:30 PM Apr 12th, 1:30 PM

Optimizing Treatment of Cytomegalovirus

Logan, UT

The current treatment to Cytomegalovirus, ganciclovir, kills neutrophils, a type of cell in the immune system. In an effort to reduce the concentration of ganciclovir, quercetin and poloxamer 188 have been added in treatment in a cellular and mouse model. This treatment has been successful, but can be further optimized by reworking the ratio of quercetin to poloxamer 188 and by adding vitamin c to prevent oxidation.