Class
Article
College
College of Agriculture and Applied Sciences
Department
Animal, Dairy, and Veterinary Sciences Department
Faculty Mentor
Zhongde Wang
Presentation Type
Poster Presentation
Abstract
The STAT2 gene encodes a protein called Signal Transducer and Activator of Transcription 2. This protein is a part of the STAT family of transcription factors, which are involved in mediating cellular responses to various cytokines and growth factors, particularly those related to the immune response. Here, we established a successful procedure for creating a STAT2 knock-out (KO) Rat that can be used for more accurate disease testing of serious human ailments such as Lupus, Polio, Herpes, RSV, and even cancer.
Location
Logan, UT
Start Date
4-8-2025 11:30 AM
End Date
4-8-2025 12:20 PM
Included in
Creating a STAT2 Knock-Out Rat With CRISPR/Cas9 Using i-GONAD
Logan, UT
The STAT2 gene encodes a protein called Signal Transducer and Activator of Transcription 2. This protein is a part of the STAT family of transcription factors, which are involved in mediating cellular responses to various cytokines and growth factors, particularly those related to the immune response. Here, we established a successful procedure for creating a STAT2 knock-out (KO) Rat that can be used for more accurate disease testing of serious human ailments such as Lupus, Polio, Herpes, RSV, and even cancer.