Class

Article

College

College of Science

Department

Biology Department

Faculty Mentor

Robert Schaeffer

Presentation Type

Poster Presentation

Abstract

Human sciences and medicine have continually been advancing, and taken off in the last few centuries. This has included the development of many new medicines, antibiotics, and disinfectants. Antibiotics have to be able to survive and perform its duty within the human body, despite the changes in pH that occur naturally within the body in response to stimuli (Cotter, 2003). If a bacteria is unable to adapt to the pH environment of the human body in which it is placed, it will not be able to survive and continue to reproduce. The bacteria may be able to adapt via membrane changes and differing metabolic processes (Percival, 2014).The isolate, SP25-LAH-13, was discovered to be Streptomyces narbonesis, a spore-forming, gram-positive bacteria which has shown to have antimicrobial properties (Bacdive, 2024). If those properties would be able to be used as antibiotics, then they, too, must be able to survive human pH environments. The experiment tests the ability of S. narbonesis to survive in stimulated gastric environments. There have been other experiments involving S. narbonesis properties (Han et al., 2012), that allow for the prediction that it will be able to grow in environments of different pHs, and therefore can be a useful resource in future antibiotics.

Location

Logan, UT

Start Date

4-8-2025 10:30 AM

End Date

4-8-2025 11:20 AM

Share

COinS
 
Apr 8th, 10:30 AM Apr 8th, 11:20 AM

Gastric Survivability of Streptomyces Narbonensis

Logan, UT

Human sciences and medicine have continually been advancing, and taken off in the last few centuries. This has included the development of many new medicines, antibiotics, and disinfectants. Antibiotics have to be able to survive and perform its duty within the human body, despite the changes in pH that occur naturally within the body in response to stimuli (Cotter, 2003). If a bacteria is unable to adapt to the pH environment of the human body in which it is placed, it will not be able to survive and continue to reproduce. The bacteria may be able to adapt via membrane changes and differing metabolic processes (Percival, 2014).The isolate, SP25-LAH-13, was discovered to be Streptomyces narbonesis, a spore-forming, gram-positive bacteria which has shown to have antimicrobial properties (Bacdive, 2024). If those properties would be able to be used as antibiotics, then they, too, must be able to survive human pH environments. The experiment tests the ability of S. narbonesis to survive in stimulated gastric environments. There have been other experiments involving S. narbonesis properties (Han et al., 2012), that allow for the prediction that it will be able to grow in environments of different pHs, and therefore can be a useful resource in future antibiotics.